False-negative of RT-PCR and prolonged nucleic acid conversion in COVID-19: Rather than recurrence.
Identifieur interne : 000643 ( 2020/Analysis ); précédent : 000642; suivant : 000644False-negative of RT-PCR and prolonged nucleic acid conversion in COVID-19: Rather than recurrence.
Auteurs : Ai Tang Xiao ; Yi Xin Tong ; Sheng ZhangSource :
- Journal of medical virology [ 1096-9071 ] ; 2020.
Abstract
A novel coronavirus (COVID-19) pandemic cause by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) threatens the world. We read with interest the recent report by Li et al. that included 610 patients with Coronavirus Disease 2019 (COVID-19). They reported a high false-negative rate of real-time reverse transcription polymerase chain reaction (RT-PCR) results for SARS-CoV-2 detection. In addition, recent report regarding SARS-CoV-2 "turn positive" in recovered cases with COVID-19 were published. Here, we studied the characteristics of nucleic acid conversion for SARS-CoV-2 from 70 COVID-19 patients. We found that 15 (21.4%) patients experienced a "turn positive" of nucleic acid detection by RT-PCR test for SARS-CoV-2 after two consecutive negative results, which may be related to the false negative of RT-PCR test and prolonged nucleic acid conversion This article is protected by copyright. All rights reserved.
DOI: 10.1002/jmv.25855
PubMed: 32270882
Affiliations:
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We read with interest the recent report by Li et al. that included 610 patients with Coronavirus Disease 2019 (COVID-19). They reported a high false-negative rate of real-time reverse transcription polymerase chain reaction (RT-PCR) results for SARS-CoV-2 detection. In addition, recent report regarding SARS-CoV-2 "turn positive" in recovered cases with COVID-19 were published. Here, we studied the characteristics of nucleic acid conversion for SARS-CoV-2 from 70 COVID-19 patients. We found that 15 (21.4%) patients experienced a "turn positive" of nucleic acid detection by RT-PCR test for SARS-CoV-2 after two consecutive negative results, which may be related to the false negative of RT-PCR test and prolonged nucleic acid conversion This article is protected by copyright. All rights reserved.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Tong, Yi Xin" sort="Tong, Yi Xin" uniqKey="Tong Y" first="Yi Xin" last="Tong">Yi Xin Tong</name><name sortKey="Xiao, Ai Tang" sort="Xiao, Ai Tang" uniqKey="Xiao A" first="Ai Tang" last="Xiao">Ai Tang Xiao</name><name sortKey="Zhang, Sheng" sort="Zhang, Sheng" uniqKey="Zhang S" first="Sheng" last="Zhang">Sheng Zhang</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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